Anna Greka is a physician-scientist, a Professor at Harvard Medical School and Mass General Brigham, and a Core Institute Member of the Broad Institute of MIT and Harvard, where she also serves as a member of the institute's Executive Leadership Team.  In her laboratory, Anna spearheads research aimed at understanding the fundamental mechanisms of cellular dysfunction in genetic diseases with a focus on membrane proteins. Leading multidisciplinary teams of scientists, Anna and her team have uncovered opportunities to target convergent "nodal" biological pathways that cause diseases in unexpectedly diverse cell types and organs (i.e. the kidney, the eye and the brain). Many of these discoveries are making their way to clinical trials in patients, with promising results.Â