Every weekday, the CNBC Investing Club with Jim Cramer releases the Homestretch — an actionable afternoon update, just in time for the last hour of trading on Wall Street. Markets: Stocks were accelerating to the downside Tuesday afternoon. The S & P 500 fell more than 1%. The Nasdaq dropped nearly 2%, with tech stocks under pressure on concerns about lofty valuations after a big run. Despite these declines, the S & P 500 was only off about 1.5% from its record closing high one week ago. Drug deal : Eli Lilly shares were modestly higher in Tuesday's down market on reports that the company may soon strike a deal with the Trump administration over GLP-1 drug pricing. Lilly and rival Novo Nordisk could offer reduced prices for the lowest doses of its GLP-1 drugs under the TrumpRX plan, according to Endpoints News, a biotech publication. That would be in exchange for obesity coverage in Medicare and Medicaid programs. We'll see what happens over the next few days. If any drugmaker were in a position to make a deal with the White House, Eli Lilly would be the one. After all, the pharmaceutical giant has committed tens of billions of dollars to boost its U.S. manufacturing footprint. Value unlock: It's day two of the DuPont separation, and the early returns have been promising. Both new DuPont and spinoff Qnity Electronics were on track Tuesday to post back-to-back positive sessions. They have also seen their valuations trade closer to peers. On a pre-spin basis, DuPont closed at $81.65 last Friday. If you take Qnity's Tuesday afternoon stock price, multiply it by the one-for-two spin terms, and then add that into the new DuPont, the combined value is around $88 per share. That's good for a move of about 8% higher in an otherwise down market. Great news for us: the sum-of-the-parts valuation thesis from DuPont's spin is playing out like we hoped. Looking ahead, DuPont will post quarterly earnings on Thursday. Qnity management will provide a business update after Thursday's close. Up next: It's an important AI earnings night with Advanced Micro Devices , Arista Networks , Astera Labs , and Super Micro Computer all scheduled to report. Some other key earnings are Axon Enterprise , Cava, Toast , and Pinterest. Companies set to release results before Wednesday's opening bell include Novo Nordisk, McDonald's , Humana , Unity, and Sportradar . Investors will also get the October ADP employment report on Wednesday morning. It's an important reading since economic data has been scarce due to the government shutdown. Private employer jobs are expected to have increased by 37,500, according to consensus estimates on FactSet. That would be a notable improvement from ADP's 32,000 job decline in September. (See here for a full list of the stocks in Jim Cramer's Charitable Trust.) As a subscriber to the CNBC Investing Club with Jim Cramer, you will receive a trade alert before Jim makes a trade. Jim waits 45 minutes after sending a trade alert before buying or selling a stock in his charitable trust's portfolio. If Jim has talked about a stock on CNBC TV, he waits 72 hours after issuing the trade alert before executing the trade. THE ABOVE INVESTING CLUB INFORMATION IS SUBJECT TO OUR TERMS AND CONDITIONS AND PRIVACY POLICY , TOGETHER WITH OUR DISCLAIMER . NO FIDUCIARY OBLIGATION OR DUTY EXISTS, OR IS CREATED, BY VIRTUE OF YOUR RECEIPT OF ANY INFORMATION PROVIDED IN CONNECTION WITH THE INVESTING CLUB. NO SPECIFIC OUTCOME OR PROFIT IS GUARANTEED.
