Asia-Pacific markets were mixed after U.S. Federal Reserve Chairman Jerome Powell forecast more rate hikes this year, saying that "the process of getting back down to 2% has a long way to go."
"Nearly all FOMC participants expect that it will be appropriate to raise interest rates somewhat further by the end of the year,"Â Powell said in remarks prepared for testimony before the House Financial Services Committee.Â
In Japan, the Nikkei 225 closed down 0.92% at 33,264, dragged by electronic stocks, while the Topix ended up marginally at 2,296.5.
South Korea's Kospi closed up 0.43%, snapping three straight days of losses and closing at 2,593.7. The Kosdaq closed marginally higher at 876.38.
Australia's S&P/ASX 200 led losses in the region and slid 1.63%, its largest single-day decline in June, closing at 7,195.5.
Elsewhere, markets in Hong Kong, mainland China and Taiwan are closed for a holiday Thursday.
Separately, crypto prices also surged in the last 24 hours, with bitcoin breaking above the $30,000 mark for the first time since April 26. Ether climbed to breach the $1,900 mark, its highest level since May 7.
Overnight in the U.S., all three major indexes fell for a third-straight day, with the Nasdaq Composite seeing the largest loss and sliding 1.21%. The Dow Jones Industrial Average was lower by 0.3%, and the S&P 500 dropped 0.52%.
— CNBC's Sarah Min and Tanaya Macheel contributed to this report
Correction: This story has been updated to reflect that markets in Hong Kong were closed on Thursday for a holiday.

